Structural and functional analysis of a family-3 N-acetylmuramyl-L-alanine amidase from the Gram-negative oral pathogen Actinobacillus actinomycetemcomitans
Williams* MA, Carletti* E, Henderson B, Okorokov AL, Bagneris C Harris R, Ladbury JE and Ward JM (2006). Submitted.

Conformational diversity in the TPR domain-mediated interaction of protein phosphatase 5 with Hsp90
Cliff MJ, Harris R, Barford D, Ladbury+ JE and Williams+ MA (2006). Structure, in press.

NMR assignment of the apo and peptide-bound SH2 domain from the Rous sarcoma viral protein Src.
Taylor* JT, Fawaz* RR, Ababou A, Williams+ MA & Ladbury +JE (2005). Journal of Biomolecular NMR 32, 339.

Distinct spatial and temporal response of Lck/ZAP70 interaction to different extracellular stimuli.
Ahmed Z, BeetonCA, Williams MA, Clements D, Baldari CT and Ladbury JE (2005).  J. Mol. Biol. 353, 1001-1010.

Molecular recognition via coupled folding and binding in a TPR domain
Cliff MJ, Williams MA, Brooke-Smith J, Barford D and Ladbury JE (2005). J. Mol. Biol. 346,717-732.

Structure of auto-inhibited protein phosphatase 5 reveals mechanisms of TPR-mediated enzyme regulation
Yang J, Roe SM, Cliff MJ, Williams MA, Ladbury JE, Cohen PTW and Barford D (2005).  EMBO J. 24, 1-10.

Heat capacity effects of water molecules and ions at a protein-DNA interface
Bergqvist S, Williams MA, O'Brien R and Ladbury JE (2004). J. Mol. Biol. 336, 829-842.

Halophilic adaptation of protein-DNA interactions
Bergqvist S, Williams MA, O'Brien R and Ladbury JE (2003). Biochem. Soc. Trans. 31, 677-680.

Refinement of protein structures in explicit solvent.
Linge JP, Williams MA, Spronk CAEM, Bonvin AM and Nilges M (2003). Proteins: Struct. Funct. Gen. 50, 496-506.

Backbone Assignment of the 25kD N-terminal ATPase domain from the Hsp90 molecular chaperone.
Salek* RM, Williams* MA, Prodromou C, Pearl LH and Ladbury JE (2002). J. Biomol NMR. 23, 327-328.

Reversal of protein halophilicity by limited mutation strategy.
Bergqvist S, Williams MA, O'Brien R and Ladbury JE (2002).  Structure 10, 629-637.

The Bioinformatics Template Library - generic components for biocomputing.
Pitt* WR, Williams*+ MA, Steven M, Sweeney B, Bleasby AJ and Moss+ DS (2001).  Bioinformatics 17, 729-737.

The solution structure of the disulphide-linked homodimer of the human trefoil protein TFF1.
Williams MA, Westley BR, May FEB and Feeney J (2001).  FEBS Lett. 493, 70-74.

High-resolution solution structure of human pNR-2/pS2: a single trefoil motif protein.
Polshakov* VI, Williams* MA,  Gargaro AR, Frenkiel TA, Westley BR, Chadwick MP, May FEB and Feeney J (1997).  J. Mol. Biol. 267, 418-432 .

Modelling protein unfolding: hen egg-white lysozyme.
Williams MA, Thornton JM and Goodfellow JM (1997). Protein Engineering 10, 895-903.

Modelling protein unfolding: a solvent insertion protocol.
Goodfellow JM, Knaggs M, Williams MA and Thornton JM (1996). Faraday Discussions 103, 339-347.

Calculation of one-electron reduction potentials for nitroheterocyclic hypoxia-selective agents.
Beveridge AJ, Williams M and Jenkins TC (1996). J. Chem. Soc., Faraday Transactions 92, 763-768.

Protein hydration, stability and unfolding.
Knaggs M, Williams M and Goodfellow JM(1995). Biochem. Soc. Trans. 23, 711-715.

New methods for the analysis of the protein-solvent interface.
Goodfellow JM, Pitt WR, Smart OS and Williams MA (1995). Computer Physics Communications 91, 321-329.

Buried waters and internal cavities in monomeric proteins.
Williams MA, Goodfellow JM and Thornton JM (1994). Protein Science 3, 1224-1235.

(* authors contributing equally to this work, + joint corresponding author)
 

Reviews

The extended interface: measuring non-local effects in biomolecular interactions
Ladbury+ JE and Williams+ MA (2004). Current Opinion in Structural Biology 14, 562-569

Molecular dynamics.
Goodfellow JM and Williams MA (1992). Current Opinion in Structural Biology 2, 211-216.
 

Book Chapters

Application of isthermal titration calorimetry in exploring the extended interface.
Ladbury JE and Williams MA (2006). In " Protein Interactions: Biophysical Approaches for the Study of Multi-Component Systems". Editor: P. Schuck , in press.

Hydrogen bonds in protein-ligand complexes
Williams+ MA and Ladbury+ JE (2003). In `Molecular Recognition in Protein-Ligand Interactions' ed. H-J Boehm & G Schneider, John Wiley-VCH, New York.

Introduction to computer simulation: Methods and applications.
Goodfellow JM and Williams MA (1994). In `Computer Simulation in Biology' ed. Goodfellow JM, VCH, Weinheim.

Applications of free energy calculations.
Williams MA, Saqi MAS and Goodfellow JM (1990). In `Molecular Dynamics' ed JM Goodfellow, MacMillan Press, London.