F XI Deficiency Mutation Database©
Mutation Maps
Sequence Map

All amino acids that are hghlighted in red have associated mutations within the database. More information on each codon can be gained by clicking it. This display is automatically generated and represents all the coding mutations within FXI

CVTQLLKDTC FEGGDITTVF TPSAKYCQVV CTYHPRCLLF TFTAESPSED PTRWFTCVLK      60
DSVTETLPRV NRTAAISGYS FKQCSHQISA CNKDIYVDLD MKGINYNSSV AKSAQECQER      120
CTDDVHCHFF TYATRQFPSL EHRNICLLKH TQTGTPTRIT KLDKVVSGFS LKSCALSNLA      180
CIRDIFPNTV FADSNIDSVM APDAFVCGRCTHHPGCLFF TFFSQEWPKE SQRNLCLLKT      240
SESGLPSTRKKSKALSGFS LQSCRHSIPV FCHSSFYHDT DFLGEELDIV AAKSHEACQK      300
LCTNAVRCQF FTYTPAQASC NEGKGKCYLK LSSNGSPTKI LHGRGGISGY TLRLCKMDNE      360
CTTKIKPRIV GGTASVRGEW PWQVTLHTTS PTQRHLCGGS IIGNQWILTAHCFYGVESP      420
KILRVYSGIL NQSEIKEDTS FFGVQEIIIH DQYKMAESGY DIALLKLETT VNYTDSQRPI      480
CLPSKGDRNV IYTDCWVTGW GYRKLRDKIQ NTLQKAKIPL VTNEECQKRY RGHKITHKMI      540
CAGYREGGKD ACKGDSGGPL SCKHNEVWHL VGITSWGEGC AQRERPGVYT NVVEYVDWIL      600
EKTQAV

Click here to see Molecular Maps from the O'Connell et al, 2005 Homology Model Study