FH aHUS Mutation Database ©
Basic Search

There are currently 74 Factor H mutations, 10 Factor I mutations and 25 MCP mutations linked with HUS patients within this database.
There are also 5 mutations within FH that are associated with MPGN patients.

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  • Mutations in FH, FI and MCP can be retrieved by codon number. Codons are numbered starting from +1 corresponding to the inital Met residue. Numbering with respect to the mature protein is also supported in the search and is shown in the results in parenthesis.
  • Mutations for each domain of FH, FI or MCP can also be retrieved.
  • For faster searches do not include JMol display output.
  • Protein:
    Enter Codon Number:
    Or Choose Domain:
    Include JMOL Display
  • For more complex queries, for example to retrieve mutations over a range of domains and by phenotypic information;