Basic Search
There are currently 74 Factor H mutations, 10 Factor I mutations and 25 MCP mutations linked with
HUS patients within this database.
There are also 5 mutations within FH that are associated with MPGN patients.
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- Mutations in FH, FI and MCP can be retrieved by codon number. Codons are numbered starting from +1 corresponding to the inital Met residue. Numbering with respect to the
mature protein is also supported in the search and is shown in the results in parenthesis.
- Mutations for each domain of FH, FI or MCP can also be retrieved.
- For faster searches do not include JMol display output.
- For more complex queries, for example to retrieve
mutations over a range of domains and by phenotypic information;